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“SEE-DRUG ” is a FP7 - RESEARH POTENTIAL project that aims to the upgrade the Structural Biology capacities of UPAT and to the Establishment of a Center of Excellence for Structure-Based Drug Target chracterization efforts in South-Eastern EU region.
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“SEE-STRUCT” is structure-oriented module of SEE-DRUG project and aims to the structural elucidation of proteins, enzymes and other interesting drug-targets. The tools offered for these efforts are a state-of-the-art high field NMR instrument of 700 MHz equipped with a highly sensitive probe and crystallization robot.
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“SEE-PROT” & “SEE-PHARM” are the protein production and the preclinical evaluation of molecules, modules of SEE-DRUG project. The tools offered for these efforts are protein production and characterization facilities an upgraded confocal microscope, an intravital microscope and myographs.
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High sensetivity probe
Studies in solution
3D Structure determination, mobility, protein-protein interaction, protein-drug interactions
In-cell imaging
Leica Microscope
Tandem Scanner
Additional laser
Sub-cellular ablation in live cells, protein-complexes, protein drug interactions in vivo
Crystal growth
Crystalization trials
Fast & efficient
Crystal growth optimization, screen of protein targes in paraller with NRM Spectroscopy
intravital Microscope
In vivo
Ex vivo
Drug screening for anti-inflammatory compounds, evaluation of vasoactive compounds

Stuctural Biology
NMR & Xray
2H/13C/15N labeling
Selective labeling
Conformation dynamics, Modeling Structure determination, 3D solutions & crystal models, Bioinformatics
Molecular Biology
Biochemical pathways
Protein production
High-yield protein expression, labeling & isolation for structural studies, protein biochemistry
In-cell studies
Functional imaging
Light Microscopy
FRET measurements
Studies of biomolecular functions through Advanced Light Microscopy, Sub-cellular ablations
Vascular Biology
Cell-based assays
Signaling pathways
Monitoring cell processes (migration. proliferation, apoptosis), in vivo & ex vivo assays

Expertise Exchange
Knowledge transfer
Best practices
New applications
Exchange of researchers between UPAT and partnering organizations - EU Centers of excellence
Structural Biology
Workshops and scientific meetings will be organized at UPAT, Advanced training course in NMR
Biomolecular NMR
Life Sciences
Invited talks, Meeting participation & Poster presentations by SEE-DRUG members
Brokerage Events
Meet the expers
Links with industry
Regional Authorities
Colloquia with invited speakers from academia or industry and private sector stakeholders

Press Releases

The SEEDRUG project and its activities have been announced many times during the first 24-27 months of the project (01/2012 -03/2014, presented and commented in a large number of local and national newspapers’ editions (~20 editions), through a UPAT’s Press Release, National Documentation Center’s press release and  University’s web-site and others.

Among the most important advertisement or promotion activities of the SEEDRUG project one should mention the:

(a) presentation of the SEEDRUG project (was selected among various REGPOT projects) at WIRE 2012 (The Week of Innovative Regions 2012) at Krakow, Poland at June 4-5 2012 (Presentation by G.A. Spyroulias).

(b) presentation of the two SEEDRUG project by two consortium Members, the Assoc Prof Stavros Taraviras from the UPAT’s School of Medicine & the Assoc Prof Georgios Spyroulias (Coordinator, Dept of Pharmacy, UPAT) at the 1st Health Forum, to a broad audience in Patras, including medical doctors and scientists working in SMEs, private labs in the fields of Biochemical analysis, Diagnosis and citizens of Patras.

(c) presentation of the Inauguration of the SEEDRUG Biomolecular NMR facility (11 October, 2013) by a number of National & local newspapers and the visit and particvipation at this event of the Nobel Laureate in Chemistry 2002, Prof Kurt Wuthrich. The participation of Prof Kurt Wuthrich at this SEEDRUG event was also presented at December Issue of the Newsletter published by the Swiss Embassy at Athens.

(d) presentation of the SEEDRUG project and the Biomolecular NMR Facility at the new building of the UPAT’s Department of Pharmacy at the Dods Parliamentary Magazine. The presentation was published at the January issue of the Dods magazine where the magazie has an extended section related with Greek EU Presidency (first half of 2014).

(e) presentation of the activities of the SEEDRUG project and the Biomolecular NMR group at the Department of Pharmacy, by the Greek Ministry of Education (videos are available at the follow link: )

(f) Press article for the Honorary doctorate of prof. Kurt Wurthrich

(g) Press article for the See-Drug Conference

Upcoming Events

Hot off the Press

porn /div> The NMR Structure of ARKADIA RING Domain (Proteins 2012, 50, 1484-89)

H2S and NO in angiogenesis & vasodilatation (PNAS 2012 in the press)

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Journal Club

  • 01 Jan 2012 Starting data of SEE-DRUG project

  • 23 Feb 2012 Kick-off meeting

  • 23 Apr2012 External Advisory Board meeting

  • 29 Apr 2013 700MHz NMR installed